I am looking to paint some black nylon wheels which are for my nitro rc truck. I am looking for the most durable paint since i run it off road. I am looking to use spray cans since i do not have a paint gun.

any recommendations would be appreciated thanks

Tough to achieve with rattle cans. You might be able to dip them in automotive paint but it will be expensive.

Or go to a good autobody supply shop and have them load a special activated aerosol can with catalyzed automotive paint. Not cheap either but way better than hardware store rattle cans.

There's a good reason they make so many gears and bushings out of nylon. It is considered a "self lubricating" kind of plastic. Nothing really wants to stick to it and colors are almost always "cast" in to the part. Chris is correct, your only hope would be some type of auto grade catalytic coating. Rattle can stuff is a waste of money.