What is the best way to strip some flaking color matched door handles? Leaning towards chemical but unsure of what to use

Are the handles metal or plastic?

What brand/model car? (Important because different manufacturers use different paints on things like door handles and some plastics)

What style of handles? Pictures would be best.

Be careful of stripper on plastic door handles.
Some will dissolve quickly, I learned the hard way.

They are just black plastic handles on a 4th generation ram, hoping to save some time rather than sanding everything off of them

Even if there is not obvious deformation caused by using chemicals on those handles the stuff can still penetrate into the surface causing micro bubbling in any subsequent coating process. If it is a common enough part I'd just replace them....

strangely enough brake fluid does a great job to remove paint from most plastic parts.
brake fluid will attack some plastics but the only plastic I have had it attack is styrene and most vehicles don't use styrene plastics.
you can buy new low cost brake fluid for a few dollar.
owning race cars and a race shop we have an abundance of used brake fluid we get from flushing cars brake systems and the old fluid also works great.
just drop the part into the fluid let it soak and depending on the paint it will take anywhere from an hour to over night to strip a part.
once the paint is lifting off we take the garden hose and wash the part/s off. this will also remove the lifting paint and wash the part for cleaning with dawn dish soap and then pre paint cleaner.